• Diettbehandling av farmakoresistent epilepsi hos barn 

      Gundersen, Astrid Julie; Hamidi, Marve (Bachelor thesis, 2019)
      Bakgrunn: Bacheloroppgaven har undersøkt om ketogendiett kan ha en positiv effekt hos barn med farmakoresistent epilepsi. Ketogen diett har blir brukt som behandling for pasienter med epilepsi tidlig på 1900-tallet og er ...
    • Hematology reference intervals in 6-12-year-old children: the health-oriented pedagogical project (HOPP) 

      Strand, Martin Frank; Fredriksen, Per Morten; Lindberg, Morten (Peer reviewed; Journal article, 2022)
      Reference intervals are essential for correct interpretation of laboratory test results, supporting clinicians in distinguishing between healthy and sick individuals. The present study aims to establish pediatric reference ...
    • Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines 

      Mygland, Line; Mahmuda, Shoshy; Strand, Martin Frank; Olsen, Petter Angell; Aizenshtadt, Aleksandra; Lund, Kaja; Solberg, Nina; Lycke, Eric Maximilian; Thorvaldsen, Tor Espen; Espada, Sandra; Misaghian, Dorna; Page, Christian Magnus; Agafonov, Oleg; Nygård, Ståle; Chi, Nai-Wen; Lin, Eva; Tan, Jenille; Yu, Yihong; Costa, Mike; Krauss, Stefan; Waaler, Jo (Peer reviewed; Journal article, 2021)
      Small-molecule tankyrase 1 and tankyrase 2 (TNKS1/2) inhibitors are effective antitumor agents in selected tumor cell lines and mouse models. Here, we characterized the response signatures and the in-depth mechanisms for ...
    • MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition 

      Solberg, Nina; Melheim, Maria; Strand, Martin Frank; Olsen, Petter Angell; Krauss, Stefan (Journal article; Peer reviewed, 2019-02-01)
      The majority of colorectal cancers are induced by subsequent mutations in APC and KRAS genes leading to aberrant activation of both canonical WNT and RAS signaling. However, due to induction of feedback rescue mechanisms ...
    • A school-based physical activity intervention on psychosocial health outcomes among 11- and 12-year-olds – HOPP-project 

      Tennfjord, Merete Kolberg; Strand, Martin Frank; Østby, Nora; Harbø, Kristin Margrethe Tange; Fredriksen, Per Morten (Peer reviewed; Journal article, 2022)
      The purpose was to investigate the effect of a school-based physical activity (PA)-intervention among 11- and 12-year-olds (6th- and 7th graders) across 4 years. Seven primary schools in Horten municipality in Norway ...
    • Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models 

      Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina; Olsen, Petter Angell; Aizenshtadt, Aleksandra; Fauskanger, Marte; Lund, Kaja; Mahmuda, Shoshy (Brinch, Shoshy Alam); Lycke, Eric Maximilian; Dybing, Elisabeth; Nygaard, Vegard; Bøe, Sigurd; Heintz, Karen Marie; Hovig, Eivind; Hammarström, Clara Louise; Corthay, Alexandre; Krauss, Stefan (Peer reviewed; Journal article, 2020)
    • Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models 

      Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina; Olsen, Petter Angell; Aizenshtadt, Aleksandra; Fauskanger, Marte; Lund, Kaja; Brinch, Shoshy Alam; Lycke, Max; Dybing, Elisabeth; Nygaard, Vegard; Bøe, Sigurd; Heintz, Karen Marie; Hovig, Eivind; Hammarström, Clara Louise; Corthay, Alexandre; Krauss, Stefan (Peer reviewed; Journal article, 2020)
      The development of immune checkpoint inhibitors represents a major breakthrough in cancer therapy. Nevertheless, a substantial number of patients fail to respond to checkpoint pathway blockade. Evidence for WNT/β-catenin ...